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STEMCELL Technologies Anti-Human CD3 Antibody, Clone OKT3, Size: 100 µg
Supplier: STEMCELL Technologies 1000287
Clone OKT3 is a mouse monoclonal antibody that reacts with an extracellular conformational epitope on the ~20 kDa CD3ε subunit of the human T cell receptor (TCR)/CD3 complex, which is expressed on the surface of ~95% of mature T cells and NKT cells, and variably on thymocytes. Verified for use with flow cytometry assays, use this antibody in applications requiring the detection of CD3. The OKT3 antibody recognizes an epitope that is expressed when the CD3ε subunit associates with either CD3γ or CD3δ, and binding of the antibody can induce T cell activation. Because of its immunosuppressive properties in vivo, the OKT3 antibody has proven useful in treating allograft rejection. Clone OKT3 is widely used for phenotyping human T cells, and it has been observed to block the binding of anti-CD3 antibody clones SK7 and UCHT1. Visit STEMCELL.com for more information and related products.
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