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STEMCELL Technologies Mouse Recombinant IL-22, Size: 10 ug
Supplier: STEMCELL Technologies 78039.1
Interleukin 22 (IL-22) is a class 2 a-helical cytokine that signals through the class 2 cytokine receptor and activates the JAK/STAT pathway. IL-22 is secreted by Th1 Th2 Tc22 and γδ T cells dendritic mast and NK cells. It stimulates expression of antimicrobial peptides from epithelial cells thus hindering bacterial infections. Depending on the interactions with other cytokines IL-22 can either promote inflammation or prevent tissue destruction by regulating host defense and tissue homeostasis at barrier surfaces (Sonnenberg et al.).
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