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STEMCELL Technologies Mouse Recombinant IL-3, Size: 1000 ug
Supplier: STEMCELL Technologies 78042.2
Use interleukin 3 (IL-3) to promote the survival and proliferation of pluripotent hematopoietic stem cells and lineage-committed progenitor cells and their differentiation into mature cells of most lineages (Broughton et al. Immunol Rev 2012). Produced by activated T cells IL-3 is a species-specific pleiotropic cytokine that has a physiological role in inflammation and allergies by promoting the secretion of inflammatory mediators. When IL-3 binds to heterodimeric receptors containing the alpha subunit and one of either beta subunits it activates JAK/STAT MAPK and PI3K signaling pathways (Scott Begley. Int J Biochem Cell Biol 1999). Mouse recombinant IL-3 from STEMCELL comes lyophilized with ≥ 95% purity EC50 0.25 ng/mL endotoxin levels verified 1 EU/μg protein. Alternative names FGFA Fibroblast growth factor-10 Keratinocyte growth factor-2. Visit STEMCELL.com for more information.
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