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STEMCELL Technologies Mouse Recombinant Shh, Size: 1000 ug
Supplier: STEMCELL Technologies 78066.2
Sonic hedgehog (Shh) is a member of the Hedgehog family of secreted signaling proteins that has a prominent role in patterning during early mammalian development (Ho Scott). It is expressed during early embryogenesis in a variety of tissues (Finco et al.). During patterning of the central nervous system Shh directly acts on cells to specify neural cell fates regulates proliferation and survival of oligodendrocyte precursors and neural crest cells and stimulates proliferation differentiation and axon growth (Ho Scott Martí). Shh also regulates T cell differentiation and activation (Crompton et al.). Recombinant Mouse Shh is a fully biologically active molecule.
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