Invitrogen™ Mouse TLR11 Synthetic Peptide

Catalog No.	Quantity
PEP0176	50 μg

Catalog No. PEP0176 Supplier Invitrogen™ Supplier No. PEP0176

Description

Synthetic Peptide

TLR11 Synthetic Peptide, PEP-0176, from Invitrogen.

The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition (2). TLR11 does not respond to known TLR ligands but instead respond specifically to uropathogenic bacteria. TLR11-deficient mice are highly susceptible to infection of the kidneys by uropathogenic bacteria, indicating that TLR11 may play a protective role in preventing infection of internal organs of the urogenital system.

Specifications

• Gene ID (Entrez): 239081
• Species: Mouse
• Purification Method: purified
• Accession Number: Q6R5P0
• Common Name: Mouse TLR11
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Symbol: Tlr11
• Lyophilized: No
• Preservative: 0.02% sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO - research use only
• Storage Buffer: PBS