Cayman Chemical MoxIfloxacInhydrochLRIde 100mg

Supplier:  Cayman Chemical 14830100 MG

A fluoroquinolone antibiotic; active against 390 clinical isolates of various bacteria (MIC90s = ≤0.25 UG/ml), as well as clinical isolates of methicillin-susceptible and -resistant S. aureus (MIC90s = 0.12 and 2 UG/ml, respectively); an inhibitor of E. coli DNA gyrase that is selective for DNA gyrase over E. coli topoisomerase IV (IC50s = 0.51 and 38.8 mg/L, respectively, in cell-free assays); prevents S. aureus- and P. aeruginosa-induced increases in BALF neutrophil infiltration and reduces S. aureus- and P. aeruginosa-induced increases in lung CXCL1 and IL-1β levels in mouse models of bacterial pneumonia at 100 mg/kg twice per day for two days; decreases the number of lung and spleen CFUs in a mouse model of systemic M. tuberculosis infection at 100 mg/kg

Catalog No. 50-297-2697