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Medchemexpress LLC MPEP Hydrochloride | 219911-35-0 | 99.8% | 229.70 | 100 MG
SDP

Catalog No. 5000359822
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MPEP Hydrochloride is a potent, selective, noncompetitive, orally and systemically active mGlu5 receptor antagonist. It effectively inhibits quisqualate-stimulated phosphoinositide (PI) hydrolysis with an IC50 of 36 nM, and demonstrates anxiolytic-like or antidepressant-like effects. Furthermore, MPEP Hydrochloride functions as a click chemistry reagent, featuring an Alkyne group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with Azide-containing molecules.

  • Potent, selective, noncompetitive mGlu5 receptor antagonist.
  • Orally active and systemically active.
  • Exhibits anxiolytic-like or antidepressant-like effects.
  • Functions as a click chemistry reagent with an alkyne group.
  • Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions.
  • IC50 of 36 nM for inhibiting quisqualate-stimulated PI hydrolysis.

Catalog No. 50-003-59822 Supplier Medchemexpress LLC Supplier No. HY14609100MG
May include imposed supplier surcharges.
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MPEP Hydrochloride is a potent, selective, noncompetitive, orally and systemically active mGlu5 receptor antagonist. It effectively inhibits quisqualate-stimulated phosphoinositide (PI) hydrolysis with an IC50 of 36 nM, and demonstrates anxiolytic-like or antidepressant-like effects. Furthermore, MPEP Hydrochloride functions as a click chemistry reagent, featuring an Alkyne group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with Azide-containing molecules.

  • Potent, selective, noncompetitive mGlu5 receptor antagonist.
  • Orally active and systemically active.
  • Exhibits anxiolytic-like or antidepressant-like effects.
  • Functions as a click chemistry reagent with an alkyne group.
  • Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions.
  • IC50 of 36 nM for inhibiting quisqualate-stimulated PI hydrolysis.

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