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Cayman Chemical mperatrn 50mg
SDP

Catalog No. 502932742
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A furanocoumarin with diverse biological activities; decreases MCL-1 protein levels and increases mitochondrial membrane depolarization and apoptosis in R-HepG2 cells, an effect that can be reversed by overexpression of MCL-1; inhibits the growth of doxorubicin-resistant and -sensitive HepG2 cells (IC50s = 28.1 and 43.3 μM, respectively); reduces tumor growth in an R-HepG2 mouse xenograft model at 50 mg/kg; inhibits LPS-induced increases in p38 MAPK, JNK, and IκBα phosphorylation, TNF-α, IL-6, and IL-1β protein levels, and nuclear localization of NF-κB p65 in RAW 264.7 macrophages; scavenges DPPH and ABTS radicals (EC50s = 19.48 and 10.93 μM, respectively); has antibacterial, antiviral, and anticonvulsant activities

Catalog No. 50-293-2742 Supplier Cayman Chemical Supplier No. 2607050 MG
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A furanocoumarin with diverse biological activities; decreases MCL-1 protein levels and increases mitochondrial membrane depolarization and apoptosis in R-HepG2 cells, an effect that can be reversed by overexpression of MCL-1; inhibits the growth of doxorubicin-resistant and -sensitive HepG2 cells (IC50s = 28.1 and 43.3 μM, respectively); reduces tumor growth in an R-HepG2 mouse xenograft model at 50 mg/kg; inhibits LPS-induced increases in p38 MAPK, JNK, and IκBα phosphorylation, TNF-α, IL-6, and IL-1β protein levels, and nuclear localization of NF-κB p65 in RAW 264.7 macrophages; scavenges DPPH and ABTS radicals (EC50s = 19.48 and 10.93 μM, respectively); has antibacterial, antiviral, and anticonvulsant activities

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