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Cayman Chemical MPI-0479605 10mg
SDP

Catalog No. 502987287
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An inhibitor of ABHD6 (IC50 0 21 nM in Neuro2A cells) inhibits ABHD6 in a 2-AG hydrolysis assay (IC50 13 6 nM for the mouse recombinant enzyme expressed in HEK293T cells) selective for ABHD6 over DAGLB at 1 UM but inhibits LYPLA1 and LYPLA2 at 10 UM inhibits ABHD6 activity in mouse liver and brain in vivo at 5-10 and 40 mg/kg respectively inhibits nicotine-induced increases in sIPSC frequency in the rat VTA but does not reduce nicotine self-administration in rats at 200 Ug has been used as a negative control for the off-target effect of KT172 on ABHD6

Catalog No. 50-298-7287 Supplier Cayman Chemical Supplier No. 2213610 MG
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An inhibitor of ABHD6 (IC50 0 21 nM in Neuro2A cells) inhibits ABHD6 in a 2-AG hydrolysis assay (IC50 13 6 nM for the mouse recombinant enzyme expressed in HEK293T cells) selective for ABHD6 over DAGLB at 1 UM but inhibits LYPLA1 and LYPLA2 at 10 UM inhibits ABHD6 activity in mouse liver and brain in vivo at 5-10 and 40 mg/kg respectively inhibits nicotine-induced increases in sIPSC frequency in the rat VTA but does not reduce nicotine self-administration in rats at 200 Ug has been used as a negative control for the off-target effect of KT172 on ABHD6

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