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Medchemexpress LLC MPP+ (iodide) | 36913-39-0 | 99.96% | 297.14 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHYW008719

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MPP+ iodide is a toxic metabolite of the neurotoxin MPTP. It causes symptoms of Parkinson's disease in animal models by selectively destroying dopaminergic neurons in the substantia nigra. The compound is taken up by the dopamine transporter into dopaminergic neurons, where it exerts its neurotoxic action on mitochondria by affecting complex I of the respiratory chain. It is also a high-affinity substrate for the serotonin transporter (SERT).

  • Toxic metabolite of neurotoxin MPTP
  • Causes Parkinson's disease symptoms in animal models
  • Selectively destroys dopaminergic neurons in the substantia nigra
  • Taken up by the dopamine transporter
  • Exerts neurotoxic action on mitochondria by affecting complex I of the respiratory chain
  • High-affinity substrate for the serotonin transporter (SERT)

Catalog No. 50-004-51480


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