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Cayman Chemical MPPodde 100mg

Supplier: Cayman Chemical 16958100 MG

An S1P1 agonist selectively induces GTPYS binding in CHO-K1 cells expressing human or rat S1P1 (EC50s 4 and 1.5 nM respectively) over those expressing human or rat S1P3 (EC50s 20 and 7.4 UM respectively) transiently reduces blood lymphocyte levels in rats with the levels returning to baseline within 24-48 hours at 0.1 and 1 mg/kg reduces hind paw volume in a rat model of adjuvant-induced arthritis (ID50 0.44 mg/kg) decreases severity in a mouse model of EAE at 0.3 and 1 mg/kg
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