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Medchemexpress LLC MR 409 | 1445155-39-4 | 99.5% | 3395.91 | 5 MG
SDP

Supplier:  Medchemexpress LLC HYP33045MG

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MR 409 is a selected growth hormone-releasing hormone (GHRH) agonist. It demonstrates neuroprotective effects by enhancing endogenous neurogenesis and inhibits the in vivo growth of lung cancer.

  • Reduces plasma levels of IL-2, IL-6, IL-10, and TNF-α.
  • Suppresses p53 expression in BPAECs; activates JAK2, STAT3, and ERK1/2.
  • Decreases LPS-induced PGE2, 8-iso-PGF2α, LDH activity, and nitrite production.
  • Decreases LPS-induced gene expression of COX-2, NF-κB, and iNOS.
  • Stimulates endogenous neurogenesis and improves neuroplasticity.
  • Enhances neural stem cell proliferation; inhibits apoptosis.
  • Inhibits in vivo lung cancer growth.
  • Reduces nociceptive response.

Catalog No. 50-003-98797


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