Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000339013

Medchemexpress LLC MRGPRX1 agonist 1 | 2377379-39-8 | 99.95% | 100 MG
SDP

Catalog No. 5000339013
Encompass_Preferred

MRGPRX1 agonist 1 is a highly potent agonist for MRGPRX1 with an EC50 of 50 nM. It exhibits over 50-fold selectivity for δ, μ, and κ opioid receptors, showing inactivity against MRGPRC11. This compound is valuable for researching chronic pain, particularly neuropathic pain, by mitigating nociceptive transmission in the spinal cord.

  • Highly potent MRGPRX1 agonist (EC50: 50 nM)
  • Over 50-fold selectivity for δ, μ, and κ opioid receptors
  • Inactive against MRGPRC11
  • Useful for the study of chronic pain, especially neuropathic pain
  • Demonstrates good distribution to the spinal cord in male mice
  • Binding affinities (Kis) for δ-Opioid (2.47 μM), μ-opioid (3.73 μM), and κ-opioid (12.10 μM) receptors

Catalog No. 50-003-39013 Supplier Medchemexpress LLC Supplier No. HY130118100MG
May include imposed supplier surcharges.
Add to Cart
Add to Cart

missing translation for 'validMainframeMsg'

MRGPRX1 agonist 1 is a highly potent agonist for MRGPRX1 with an EC50 of 50 nM. It exhibits over 50-fold selectivity for δ, μ, and κ opioid receptors, showing inactivity against MRGPRC11. This compound is valuable for researching chronic pain, particularly neuropathic pain, by mitigating nociceptive transmission in the spinal cord.

  • Highly potent MRGPRX1 agonist (EC50: 50 nM)
  • Over 50-fold selectivity for δ, μ, and κ opioid receptors
  • Inactive against MRGPRC11
  • Useful for the study of chronic pain, especially neuropathic pain
  • Demonstrates good distribution to the spinal cord in male mice
  • Binding affinities (Kis) for δ-Opioid (2.47 μM), μ-opioid (3.73 μM), and κ-opioid (12.10 μM) receptors

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.