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Medchemexpress LLC MRK-560 | 677772-84-8 | 99.0% | C19H17ClF5NO4S2 | 50 MG
Supplier: Medchemexpress LLC HY1417450MG
MRK-560 is an orally active, brain barrier-penetrated γ-Secretase inhibitor that acts as a chemical probe. It reduces Aβ peptide in rat brain and cerebrospinal fluid. This compound decreases mutant NOTCH1 processing by selectively inhibiting PSEN1, making it suitable for studies related to Alzheimer's disease and T-cell acute lymphoblastic leukaemia (T-ALL).
- Orally active and brain barrier-penetrated
- Reduces Aβ peptide in rat brain and cerebrospinal fluid
- Decreases mutant NOTCH1 processing by selectively inhibiting PSEN1
- Useful in studies of Alzheimer's disease
- Useful in studies of T-cell acute lymphoblastic leukaemia (T-ALL)
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