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Medchemexpress LLC MRL-494 hydrochloride | 2699937-04-5 | 98.6% | 100 MG
Supplier: Medchemexpress LLC HY128773A100MG
MRL-494 hydrochloride is an antibacterial agent that acts as an inhibitor of β-barrel assembly machine A (BamA). It is impervious to efflux and the outer membrane permeability barrier, and lethally disrupts the cytoplasmic membrane. It inhibits outer membrane proteins (OMPs) biogenesis by targeting BamA, demonstrating strong anti-microbial properties against various bacteria.
- Acts as an inhibitor of β-barrel assembly machine A (BamA)
- Impervious to efflux and outer membrane permeability barrier
- Lethally disrupts the cytoplasmic membrane
- Inhibits outer membrane proteins (OMPs) biogenesis
- Strong anti-microbial properties against Gram-positive bacteria (e.g., *Staphylococcus aureus* with MIC of 12.5 μM)
- Strong anti-microbial properties against Gram-negative bacteria (e.g., *E. coli* with MIC of 25 μM)
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