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Medchemexpress LLC MRL-494 hydrochloride | 2699937-04-5 | 98.6% | 50 MG
Supplier: Medchemexpress LLC HY128773A50MG
MRL-494 hydrochloride is an antibacterial agent that functions as an inhibitor of β-barrel assembly machine A (BamA), making it impervious to efflux and the outer membrane permeability barrier. It is effective against both Gram-positive and Gram-negative bacteria, with an MIC of 12.5 μM for *Staphylococcus aureus* COL and 25 μM for *E. coli* JCM158.
- Inhibits β-barrel assembly machine A (BamA)
- Impervious to efflux and the outer membrane permeability barrier
- Exhibits strong activity against both Gram-positive and Gram-negative bacteria
- Lethally disrupts the cytoplasmic membrane
- Inhibits outer membrane proteins (OMPs) biogenesis
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