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Cayman Chemical MRSCoV NucleocapsId ProteIn

Supplier: Cayman Chemical 40878100 UG

An inhibitor of DGK-a DGK-ζ and DGK-ι (IC50s 0.0046 0.0021 and 0.0026 UM respectively) selective for these DGKs over DGK-B DGK-Y and DGK-K (IC50s 1 0.68 and 4.6 UM respectively) increases IFN-Y levels and ERK phosphorylation in isolated human whole blood (EC50s 0.28 and 0.52 UM respectively) increases the proliferation of CD8 T cells (EC50 0.065 UM) which express DGK-a and DGK-ζ but not DGK-ι increases the frequency of CD69 CD8 T cells in combination with SIINFEKL in OT I mice
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