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Medchemexpress LLC HY-120877 5mg Medchemexpress, MRT199665 CAS:1456858-57-3 Purity:>98%
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Supplier:  Medchemexpress LLC HY1208775MG

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Medchemexpress, HY-120877 5mg MRT199665 CAS:1456858-57-3 MRT199665 is a potent and ATP-competitive, selective MARK/SIK/AMPK inhibitor with IC50s of 2/2/3/2 nM, 10/10 nM, and 110/12/43 nM for MARK1/MARK2/MARK3/MARK14, AMPKα1/AMPKα2, and SIK1/SIK2/SIK3, respectively. MRT199665 causes apoptosis in MEF2C-activated human acute myeloid leukemias (AML) cells. MRT199665 inhibits the phosphorylation of SIK substrate CRTC3 at S370. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

Catalog No. 50-208-0955


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