Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC MRTX-EX185 (formic) | 2988148-70-3 | 97.2% | C34H35FN6O4 | 10MG
Supplier: Medchemexpress LLC HY145962A10MG
MRTX-EX185 (formic) is a small-molecule inhibitor of KRAS with potent activity against the oncogenic G12D mutant (IC50 = 90 nM). It binds both GDP-loaded and GNP (GTP-mimetic) states of KRAS and is intended for biochemical, cellular, and tumor-model research. The compound is supplied as a purified solid (yellow to brown), with reported purity around 97.2%, molecular formula C34H35FN6O4, and molecular weight 610.68 g·mol⁻¹.
- Potent KRAS G12D inhibition (IC50 = 90 nM).
- Binds both GDP-loaded and GTP-mimetic states of KRAS.
- Applicable to in vitro and in vivo research studies.
- High reported purity, suitable for research use.
- Readily soluble in DMSO (125 mg/mL) for assay preparation.
- Stable as powder when stored at -20°C for long-term storage.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?