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Medchemexpress LLC MS402 | 1672684-68-2 | 98.4% | 100 MG
SDP

Supplier:  Medchemexpress LLC HY120000100MG

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MS402 is a BD1-selective BET bromodomain inhibitor used in research to modulate Th17 cell differentiation and inflammation in preclinical models. It is supplied as a powder and has reported activity in mouse colitis models.

  • Selective inhibition of BD1 bromodomain (reported Ki values: BRD4(BD1) 77 nM; BRD4(BD2) 718 nM; BRD3(BD1) 110 nM; BRD3(BD2) 200 nM; BRD2(BD1) 83 nM; BRD2(BD2) 240 nM).
  • Demonstrated biological activity in preclinical models, including blockade of Th17 differentiation and amelioration of colitis.
  • Provided as a powder for research use in small pack sizes suitable for laboratory studies.
  • Molecular formula C20H19ClN2O3 and molecular weight 370.83 aid compound identification and handling.

Catalog No. 50-002-33235


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