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Medchemexpress LLC Msx-122 | 897657-95-3 | 98.2% | 292.34 | 100 MG
Supplier: Medchemexpress LLC HY13696100MG
MSX-122 is an orally active partial antagonist of CXCR4, effectively inhibiting CXCR4/CXCL12 actions with an IC50 of approximately 10 nM. This compound exhibits both anti-inflammatory and anti-metastatic activities. It potently blocks the invasion of MDA-MB-231 cells in vitro and has been shown to reduce inflammation and lung fibrosis in mice, as well as blocking metastasis in experimental animal models of breast cancer.
- Orally active partial antagonist of CXCR4.
- Inhibits CXCR4/CXCL12 actions.
- Shows anti-inflammatory activity.
- Exhibits anti-metastatic activity.
- Potently blocks invasion of certain cancer cells.
- Decreases hepatic micrometastases in animal models.
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