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Medchemexpress LLC MSX-122 | 897657-95-3 | 98.2% | 292.34 | 25 MG
Supplier: Medchemexpress LLC 25MGHY13696
MSX-122 is an orally active partial antagonist of CXCR4, inhibiting CXCR4/CXCL12 actions, with an IC50 of ~10 nM.
- Anti-inflammatory activity.
- Anti-metastatic activity.
- Orally active.
- Potently blocks invasion of MDA-MB-231 cells in vitro.
- Blocks inflammation induced by carrageenan and lung fibrosis induced by bleomycin in mice.
- Blocks metastasis in an experimental animal model of breast cancer metastasis.
- Significantly decreases the numbers of hepatic micrometastases in vivo.
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