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Cayman Chemical MTP 131acetate 10mg
Supplier: Cayman Chemical 3330210 MG
A mitochondria-targeted peptide antioxidant; reduces tert-butyl hydroperoxide-induced lipid peroxidation and apoptosis in SH-SY5Y cells from 0.001 to 1 nM; reduces infarct volume, hemispheric swelling, and GSH depletion in a mouse model of MCAO-induced acute cerebral ischemia at 2 mg/kg; increases survival, improves motor function, and decreases degeneration of the lumbar spinal cord in the SOD1G93A transgenic mouse model of ALS at 5 mg/kg; reduces albuminuria, urinary hydrogen peroxide levels, and mesangial matrix accumulation, as well as preserves superoxide production, in a db/db mouse model of diabetic nephropathy
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