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Dojindo Molecular Technologies Inc Mtphagy Dye (5UG x3) is optimized for mammalian cells. No need for transfection, simply add Mtphagy Dye!
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Supplier:  Dojindo Molecular Technologies Inc MT0210

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Mitochondria plays a crucial role in cells such as production of energy for cell viability. Mitophagy was recently found to be related to Alzheimer and Parkinson disease induced by the accumulation of depolarized mitochondria. Mitophagy serves as a specific elimination system that dysfunctional mitochondria caused by oxidative stress and DNA damage are sequestered into autophagosomes, fused to lysosomes and degraded by digestion. Mtphagy Dye accumulates in intact mitochondria, is immobilized on it with chemical bonds and exhibits a weak fluorescence from the influence of surrounding conditions. When Mitophagy is induced, the damaged mitochondria fuses to lysosomes and then Mtphagy Dye emits a high fluorescence.

Catalog No. 50-190-3724


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