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ATCC MUG-Chor1; Chordoma; Human (Homo sapiens)
Supplier: ATCC CRL3219
MUG-Chor1 is a mesenchymal like cell line that was isolated in sacrum from the 2009 of a 57-year-old, White female patient with chordoma. Chordoma is a rare slow-growing tumor type and MUG-Chor1 is a relatively slow-growing cell line. MUG-Chor1 has a heterogeneous morphology consisting of physaliferous cells with mucinous intercellular substance, which represent typical chordoma features. The cells contain amplification of transcription factor T (Brachyury) that is most specific marker for chordoma, as well as loss of PTEN. This cell line was accessioned with the support of the Chordoma Foundation, a nonprofit organization working to improve the lives of chordoma patients by accelerating research to develop effective treatments for chordoma. This cell line was deposited by Beate Rinner and Bernadette Liegl.
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