Cayman Chemical MulberrosIde A 100mg

Supplier:  Cayman Chemical 27545100 MG

A phenol with diverse biological activities; inhibits rifampicin-induced pregnane X receptor-mediated P-gp luciferase reporter activity in LS174T cells from 5-20 μM; decreases expression of TNF-α, IL-1β, and IL-6, inhibits caspase-1 activation, and increases cell viability in an isolated rat cortical neuron model of oxygen-glucose deprivation-induced ischemia and reperfusion injury; topical administration reduces UVB-induced skin hyperpigmentation, levels of the melanogenesis enzymes tyrosinase, TRP-1, and MITF, and tyrosinase activity in brown guinea pig skin at 2 and 5% v/v; decreases serum levels of uric acid, creatinine, and urea nitrogen, reduces renal vacuolar and granular degeneration, and increases fractional excretion of uric acid and urinary urate excretion in hyperuricemic mice at 10, 20, and 40 mg/kg

Catalog No. 50-294-1744