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Vector Biolabs Musculin (activated B-cell factor-1) Adenovirus (Ad-Musculin)

Supplier:  Vector Biolabs 1555

Encompass

Musculin contains a bHLH motif, a putative nuclear localization signal, a glycine-rich region, and a stretch of acidic residues. MSC is capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro, and forms heterodimers with E2A proteins in vivo. MSC contains a transcriptional repression domain and is capable of inhibiting the transactivation capability of E47, an E2A protein, in mammalian cells. MSC is a downstream target of the B-cell receptor signal transduction pathway.

Catalog No. 50-004-96530


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