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Medchemexpress LLC Musk ketone | 81-14-1 | 294.31 | 100 MG
Supplier: Medchemexpress LLC HYN2045100MG
Musk ketone is a widely used artificial fragrance and a cytochrome P450 enzyme inducer. It shows mutagenic and comutagenic effects in Hep G2 cells and induces neural stem cell proliferation and differentiation in cerebral ischemia via activation of the PI3K/Akt signaling pathway. In the brain, musk ketone is neuroprotective against stroke injury through inhibition of cell apoptosis. It also inhibits the cell viability of GC cells and induces cell cycle arrest and apoptosis.
- Enhances proliferation and differentiation in neural stem cells
- Increases PI3K/Akt signaling pathway activation
- Ameliorates neurological deficit and reduces infarction and cerebral ischemic injury
- Increases CYP2B activity, protein and mRNA levels, and increases CYP1A enzyme activity
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