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Medchemexpress LLC MYF-03-176 | 2857937-59-6 | 99.72% | 410.37 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY147136

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MYF-03-176 is an orally active inhibitor of TEAD, suppressing TEAD transcriptional activity with an IC50 of 11 nM. It inhibits hippo signaling defective malignant pleural mesothelioma (MPM) cells and demonstrates strong antitumor efficacy in an MPM mouse xenograft model. The IC50 values for TEAD1, TEAD3, and TEAD4 are 47, 32, and 71 nM, respectively.

  • Orally active inhibitor of TEAD
  • Suppresses TEAD transcriptional activity with an IC50 of 11 nM
  • Inhibits hippo signaling defective malignant pleural mesothelioma (MPM) cells
  • Demonstrates strong antitumor efficacy in MPM mouse xenograft model

Catalog No. 50-003-63699


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