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Cayman Chemical MYK-461, 1642288-47-8, 10 mg

Supplier: Cayman Chemical 1921610

Molecular Formula C15H19N3O2, Purity ≥98%, Formula Weight 273.3, Synonyms: SAR439152; A cardiac myosin ATPase inhibitor (IC50 = 0.3 M); selective for cardiac myosin over skeletal myosin (IC50 = 4.7 M); slows ATPase activity of - and -myosin; reduces cardiac contractility, prevents left ventricular hypertrophy, and reverses pathologic remodeling in mouse models; relieves left ventricular outflow tract obstruction in cats.
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