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Medchemexpress LLC N'-(1,8-dimethylimidazo[1,2-a]quinoxalin-4-yl)ethane-1,2-diamine | 445430-58-0 | MFCD18089812 | 99.7% | 255.32 g·mol⁻1 | C14H17N5 | 1 MG
SDP

Catalog No. 5000243493
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BMS-345541 is a selective, cell-permeable small-molecule inhibitor of the catalytic subunits of IκB kinase (IKK). It inhibits IKK-2 with reported IC50 ≈ 0.3 μM and IKK-1 with IC50 ≈ 4 μM, binding at an allosteric site. The compound is used in biochemical and cellular studies to probe NF-κB signaling, inflammation, and related pathways.

  • Selective inhibitor of IKK catalytic subunits.
  • Potent inhibition of IKK-2 (IC50 ≈ 0.3 μM) and activity against IKK-1.
  • Allosteric site binder, useful for mechanistic studies.
  • Suitable for biochemical assays and cellular signaling experiments.
  • High purity for reproducible results.

Catalog No. 50-002-43493 Supplier Medchemexpress LLC Supplier No. HY105191MG
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BMS-345541 is a selective, cell-permeable small-molecule inhibitor of the catalytic subunits of IκB kinase (IKK). It inhibits IKK-2 with reported IC50 ≈ 0.3 μM and IKK-1 with IC50 ≈ 4 μM, binding at an allosteric site. The compound is used in biochemical and cellular studies to probe NF-κB signaling, inflammation, and related pathways.

  • Selective inhibitor of IKK catalytic subunits.
  • Potent inhibition of IKK-2 (IC50 ≈ 0.3 μM) and activity against IKK-1.
  • Allosteric site binder, useful for mechanistic studies.
  • Suitable for biochemical assays and cellular signaling experiments.
  • High purity for reproducible results.

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