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Medchemexpress LLC N-[(1R)-1-(3-cyclopentyloxyphenyl)ethyl]-3-[(2,4-dioxopyrimidin-1-yl)methoxy]propane-1-sulfonamide | 1198221-21-4 | 99.8% | 451.5 g/mol | C21H29N3O6S | 1MG
SDP

Catalog No. 5000238280
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TAS-114 is an orally active small-molecule inhibitor that dual-targets deoxyuridine triphosphatase (dUTPase) and dihydropyrimidine dehydrogenase (DPD). It has been investigated as an adjunct to fluoropyrimidine chemotherapy to enhance efficacy by modulating nucleotide metabolism and reducing catabolism of 5-fluorouracil (CAS 1198221-21-4).

  • Dual inhibition of dUTPase and DPD enhances fluoropyrimidine efficacy.
  • Oral bioavailability suitable for systemic administration.
  • Defined molecular formula and molecular weight support reproducible characterization.
  • High reported chemical purity enables reliable experimental results.
  • Appropriate for preclinical research on combination chemotherapy strategies.

Catalog No. 50-002-38280 Supplier Medchemexpress LLC Supplier No. HY1240621MG
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TAS-114 is an orally active small-molecule inhibitor that dual-targets deoxyuridine triphosphatase (dUTPase) and dihydropyrimidine dehydrogenase (DPD). It has been investigated as an adjunct to fluoropyrimidine chemotherapy to enhance efficacy by modulating nucleotide metabolism and reducing catabolism of 5-fluorouracil (CAS 1198221-21-4).

  • Dual inhibition of dUTPase and DPD enhances fluoropyrimidine efficacy.
  • Oral bioavailability suitable for systemic administration.
  • Defined molecular formula and molecular weight support reproducible characterization.
  • High reported chemical purity enables reliable experimental results.
  • Appropriate for preclinical research on combination chemotherapy strategies.

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