Medchemexpress LLC N-(2-(2-acrylamidophenyl)-4-(pyridin-4-yl)thiazol-5-yl)-2-(difluoromethyl)benzamide | 2227368-54-7 | MFCD34593626 | 99.0% | 452.46 g/mol | C25H20N6O3 | 25 MG

Supplier:  Medchemexpress LLC HY103017A25MG

Potent and selective IRAK1 inhibitor for research use. The compound inhibits IRAK1 with an apparent IC50 of 9 nM and shows no inhibition of IRAK4 at concentrations up to 10 μM. Supplied as a solid or as a DMSO solution, it provides defined solubility and storage properties.

• Potent, selective IRAK1 inhibition with an apparent IC50 of 9 nM.
• High purity (99.03%) for reliable experimental results.
• Available as solid and as 10 mM solutions in DMSO for flexible dosing.
• Molecular weight 452.46 g/mol; molecular formula C25H20N6O3.
• High solubility in DMSO (125 mg/mL) and in vivo formulation solubility ≥1.98 mg/mL under protocol conditions.
• Stable storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).

Catalog No. 50-002-47368