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Medchemexpress LLC N-(2-((5-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)phenyl)met | 2254805-62-2 | 98.6% | C23H28ClN7O3S | 10MG
SDP

Supplier:  Medchemexpress LLC HY13588710MG

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ZX-29 is a potent, selective small-molecule anaplastic lymphoma kinase (ALK) inhibitor for research use. It inhibits wild-type ALK and key resistance mutants, induces endoplasmic reticulum stress and apoptosis, and can trigger protective autophagy with reported antitumor activity in preclinical studies.

  • Potent ALK inhibition with low-nanomolar IC50s for wild-type and resistance mutants.
  • Induces endoplasmic reticulum stress and apoptosis in cellular models.
  • Promotes protective autophagy and demonstrates antitumor activity in preclinical assays.
  • High reported purity (~98.6%) suitable for laboratory research.
  • Soluble in DMSO (~50 mg/mL) with heating and sonication.
  • Store protected from light; solvent stability varies by temperature.

Catalog No. 50-002-61359


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