Medchemexpress LLC N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]propanamide | 1214265-58-3 | MFCD28015100 | 98.0% | 496.99 g·mol⁻1 | C25H29ClN6O3 | 10 MG

Supplier:  Medchemexpress LLC HY1580210MG

WZ4003 is a potent, selective small-molecule inhibitor of the NUAK family kinases used as a research tool for biochemical and cellular studies. Reported activity includes an IC50 of 20 nM for NUAK1 (ARK5) and 100 nM for NUAK2, with minimal inhibition against a broad kinase panel. Supplied as solid material or as a DMSO solution for laboratory use; manufacturer-reported purity is ~98%.

• Potent inhibition of NUAK1 (IC50 20 nM) and NUAK2 (IC50 100 nM).
• High selectivity with negligible inhibition of approximately 139 other kinases.
• Suitable for biochemical kinase assays and cellular target validation.
• Available as solid (5-200 mg) and as a 10 mM solution in DMSO.
• Manufacturer-reported purity approximately 98% and CAS 1214265-58-3.

Catalog No. 50-002-88034