Medchemexpress LLC N-[3-[[5-chloro-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]thio]phenyl]-2-propenamide | 1214265-57-2 | 99.2% | 5 MG

Supplier:  Medchemexpress LLC HY120295MG

WZ8040 is an irreversible, mutant-selective inhibitor of the epidermal growth factor receptor (EGFR) with activity against the T790M resistance mutation. It inhibits EGFR phosphorylation and is used as a laboratory research compound to study mutant EGFR signaling and inhibitor sensitivity.

• Irreversible inhibitor of EGFR T790M.
• Demonstrates substantially greater potency against mutant EGFR compared with wild-type.
• Available as solid powder and as DMSO solutions for ready-to-use applications.
• Typical purity around 99.2% as supplied.
• Soluble in DMSO (high solubility reported) and formulatable for in vivo dosing protocols.
• Store powder at -20°C for long-term stability; store stock solutions at -80°C when possible.
• Intended for research use only; not for human or veterinary use.

Catalog No. 50-002-34411