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Medchemexpress LLC N-(3-{[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)-3-[4-(dimethylamino)but-2-enamido]... | 1604810-84-5 | 98.0% | 5 MG
SDP

Catalog No. 5000231979
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THZ2 is a potent, selective covalent inhibitor of cyclin-dependent kinase 7 (CDK7) with low-nanomolar inhibitory activity (IC50 ≈ 13.9 nM). It is used in vitro and in vivo to study transcriptional regulation and oncogenic proliferation, particularly in triple-negative breast cancer models.

  • Potent CDK7 inhibition with IC50 of ~13.9 nM.
  • Selective activity in the low-nanomolar range for cellular and biochemical assays.
  • Demonstrated anti-proliferative and pro-apoptotic effects in triple-negative breast cancer models.
  • Supplied as a solid; soluble in DMSO and available in multiple pack sizes for research use.
  • Molecular formula C31H28ClN7O2, molecular weight 566.05 g/mol.

Catalog No. 50-002-31979 Supplier Medchemexpress LLC Supplier No. HY122805MG
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THZ2 is a potent, selective covalent inhibitor of cyclin-dependent kinase 7 (CDK7) with low-nanomolar inhibitory activity (IC50 ≈ 13.9 nM). It is used in vitro and in vivo to study transcriptional regulation and oncogenic proliferation, particularly in triple-negative breast cancer models.

  • Potent CDK7 inhibition with IC50 of ~13.9 nM.
  • Selective activity in the low-nanomolar range for cellular and biochemical assays.
  • Demonstrated anti-proliferative and pro-apoptotic effects in triple-negative breast cancer models.
  • Supplied as a solid; soluble in DMSO and available in multiple pack sizes for research use.
  • Molecular formula C31H28ClN7O2, molecular weight 566.05 g/mol.

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