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Medchemexpress LLC N-[4-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]phenyl]-1-(2-furanylmethyl)-5-oxo-pyrrolidinecarboxamide | 2784577-71-3 | MFCD00701047 | C24H19ClN4O4 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY15070010MM/1ML

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RLX-33 is a potent, selective, and blood-brain barrier (BBB) penetrant relaxin family peptide 3 (RXFP3) antagonist. This compound blocks relaxin-3-induced ERK1/2 phosphorylation and can prevent the stimulation of food intake induced by the RXFP3-selective agonist R3/I5 in rats, making it suitable for metabolic syndrome research.

  • Potent and selective RXFP3 antagonist
  • Blood-brain barrier penetrant
  • Blocks relaxin-3-induced ERK1/2 phosphorylation
  • Attenuates R3/I5-induced feeding
  • Good brain penetration
  • Highly protein-bound in rat plasma
  • Useful for metabolic syndrome research

Catalog No. 50-003-75644


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