Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000245116

Medchemexpress LLC N-(4-((3-chloro-4-fluorophenyl)amino)pyrido[3,4-d]pyrimidin-6-yl)-N'-(1-(dimethylamino)propan-2-yl)a | 848133-17-5 | MFCD26792555 | 99.2% | 574.05 | C31H29ClFN5O3 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1034435MG

Encompass_Preferred

HKI-357 is an irreversible small-molecule inhibitor of EGFR and ERBB2 kinases. It inhibits EGFR autophosphorylation at Y1068 and reduces downstream AKT and MAPK phosphorylation, showing potent activity in cell signaling and preclinical cancer models. Supplied as a solid research reagent for in vitro and preclinical studies.

  • Irreversible dual inhibitor of EGFR and ERBB2
  • Potent activity: EGFR 34 nM, ERBB2 33 nM
  • Suppresses EGFR Y1068 autophosphorylation and downstream signaling
  • Supplied as a solid, >99% purity (batch-dependent)
  • Suitable for kinase signaling and preclinical cancer research

Catalog No. 50-002-45116


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.