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Medchemexpress LLC N-[4-[[[(3R,4R)-1-[(2S)-2-amino-1-oxopropyl]-3-methyl-4-piperidinyl]amino]sulfonyl]-1-naphthalenyl]-2-methyl-benzamide | 850330-18-6 | >98.0% | 508.63 | C27H32N4O4S | 50MG
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Supplier:  Medchemexpress LLC HY12441650MG

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ML604086 is a small-molecule CCR8 antagonist used in research to block CCL1-CCR8 interactions. It inhibits CCL1 binding to CCR8 on circulating T cells, reduces CCL1-mediated chemotaxis, and has been characterized in cell-based assays and preclinical in vivo studies, including non-human primate models.

  • Selective CCR8 antagonist that inhibits CCL1 binding to CCR8.
  • Inhibits CCL1-mediated chemotaxis and modulates intracellular Ca2+ responses.
  • Characterized in vitro and in vivo, including primate pharmacology studies.
  • Supplied as a solid for laboratory research use.
  • Molecular weight 508.63 g·mol-1; formula C27H32N4O4S; CAS 850330-18-6.
  • Typical research-grade purity >98% with low-temperature storage recommended.

Catalog No. 50-002-35651


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