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Medchemexpress LLC N-[4-[[[(3R,4R)-1-[(2S)-2-amino-1-oxopropyl]-3-methyl-4-piperidinyl]amino]sulfonyl]-1-naphthalenyl] | 850330-18-6 | 99.8% | 508.63 g·mol^-1 | C27H32N4O4S | 25MG

Supplier: Medchemexpress LLC HY12441625MG
ML604086 is a selective small-molecule inhibitor of the chemokine receptor CCR8 developed for laboratory research. It inhibits CCL1 binding to CCR8, blocks CCL1-mediated chemotaxis, and increases intracellular Ca2+ in CCR8-expressing cells, with reported micromolar activity in vitro.
- Selective CCR8 small-molecule inhibitor for research use.
- Inhibits CCL1 binding to CCR8 and blocks chemotaxis.
- Increases intracellular Ca2+ concentrations in CCR8-expressing cells.
- Reported in vitro IC50 ~1.0-1.3 μM in CCR8 assays.
- Chemical formula C27H32N4O4S; molecular weight 508.63 g·mol⁻¹.
- Purity listed as 99.78% (supplier assay).
- Available as powder and as 10 mM solution in DMSO, with multiple pack sizes including 25 mg.
- Intended for research use only; not for human use.
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