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Medchemexpress LLC N-[4-(4-chlorophenyl)sulfonyl-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide | 677772-84-8 | MFCD09970622 | >98.0% | C19H17ClF5NO4S2 | 10MG
SDP

Supplier:  Medchemexpress LLC HY1417410MG

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MRK-560 is a PSEN1-selective γ-secretase inhibitor used as a research probe for amyloid precursor protein processing. It is orally active and brain-penetrant, and has been shown in preclinical studies to reduce amyloid-β peptide levels in brain and cerebrospinal fluid. The compound is supplied as a solid powder with documented storage and solubility recommendations for in vitro and in vivo applications.

  • Selective inhibition of PSEN1-containing γ-secretase complexes.
  • Orally active and brain-penetrant for central nervous system studies.
  • Reduces amyloid-β peptide levels in preclinical models.
  • High solubility in DMSO and multiple documented in vivo formulation options.
  • Supplied as a powder with recommended cold-storage conditions for stability.
  • Well-characterized chemical identity with published molecular and structural data.

Catalog No. 50-002-59515


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