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Medchemexpress LLC N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]urea (AST 487) | 630124-46-8 | MFCD11983171 | 98.9% | 529.56 g/mol | C26H30F3N7O2 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY1500210MG

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AST-487 is a small-molecule RET kinase inhibitor provided for laboratory research. It inhibits RET autophosphorylation and downstream signaling (reported RET IC50 ≈ 880 nM) and shows activity against FLT3 (IC50 ≈ 520 nM) and several other kinases. The compound is supplied as a solid and as a DMSO solution and is intended for research use only.

  • Inhibits RET kinase with reported IC50 ≈ 880 nM.
  • Shows activity against FLT3 with reported IC50 ≈ 520 nM.
  • Chemical formula C26H30F3N7O2; molecular weight ≈ 529.6 g/mol.
  • Available as solid quantities and as a 10 mM solution in DMSO.
  • High supplier-reported purity (98.9% by supplier specification).
  • Intended for research use only; not for clinical or human therapeutic use.

Catalog No. 50-002-86670


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