Medchemexpress LLC N-(4-benzyl-3-methyl-1,2,4-thiadiazol-5-ylidene)-N'-phenylbenzenecarboximidamide | 324579-65-9 | 99.9% | 384.50 g/mol | C23H20N4S | 10MM 1ML

Supplier:  Medchemexpress LLC HY12396710MM 1ML

RNF5 inhibitor inh-02 is a small-molecule inhibitor of the E3 ubiquitin ligase RNF5 used in research to rescue F508del-CFTR function and to study autophagy and ubiquitin-mediated proteostasis. The compound has molecular formula C23H20N4S, exact mass 384.50 g/mol, and is typically provided as a 10 mM solution in DMSO or as solid quantities for assay and synthesis work.

• Potent inhibitor of E3 ubiquitin ligase RNF5 with cell-based activity (EC50 ≈ 2.2-2.6 μM).
• Available as 10 mM solution in DMSO and as multiple solid pack sizes.
• High purity (99.9%).
• Recommended solvent for solution preparation: DMSO.
• Storage: powder -20°C (up to 3 years); in solvent -80°C (6 months) or -20°C (1 month).
• Suitable for cystic fibrosis research and studies of protein quality control and autophagy.

Catalog No. 50-002-36269