Medchemexpress LLC N-[5-({[(3-fluorophenyl)carbamoyl]amino}methyl)-2-methylphenyl]imidazo[1,2-a]pyridine-3-carboxamide | 1644069-80-6 | MFCD31567545 | 99.0% | 417.44 | C23H20FN5O2 | 1 ML

Supplier:  Medchemexpress LLC HYW01893110MM/1ML

DDR Inhibitor is a small-molecule discoidin domain receptor (DDR) inhibitor for research applications. It potently inhibits DDR2 (IC50 3.3 nM), shows partial activity against DDR1 (53% inhibition at 1.5 nM), and inhibits collagen I-induced DDR2 phosphorylation in cells (EC50 8.7 nM). Available as concentrated DMSO solution or as solid for biochemical and cell-based studies.

• Potent DDR2 inhibition (IC50 3.3 nM).
• Partial DDR1 activity (53% inhibition at 1.5 nM).
• Cell-active inhibition of collagen I-induced DDR2 phosphorylation (EC50 8.7 nM).
• Available as 10 mM solution in DMSO or as solid quantities.
• High reported purity (>99% by HPLC) with COA available.
• Suitable for biochemical and cell-based DDR signaling studies.

Catalog No. 50-003-00836