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Medchemexpress LLC N-[5-amino-1,2,3,4-tetrahydro-1-[4-(trifluoromethyl)phenyl]-3-quinolinyl]-2-propenamide | 2766575-48-6 | MFCD22417285 | 99.8% | 361.36 | C19H18F3N3O | 10 MG
SDP

Supplier:  Medchemexpress LLC HY15533810MG

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SWTX-143 is a covalent, irreversible inhibitor of the YAP/TAZ-TEAD transcriptional complex developed for research. It binds the palmitoylation pocket of TEAD isoforms and suppresses YAP/TAZ-TEAD transcriptional activity, and has demonstrated oral activity in preclinical studies. The compound is supplied as a high-purity solid intended for biochemical and cell-based research applications.

  • Covalent, irreversible inhibitor of YAP/TAZ-TEAD.
  • Binds the palmitoylation pocket of TEAD isoforms.
  • Inhibits YAP/TAZ-TEAD transcriptional activity.
  • Demonstrated oral activity in preclinical studies.
  • High reported purity (about 99.8%).
  • Supplied as a white to off-white solid.
  • Available in milligram-scale packages for laboratory research.
  • Suitable for biochemical and cell-based assays.

Catalog No. 50-002-85876


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