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AdipoGen N-Acetyl-D-glucosamine
SDP

Supplier:  AdipoGen AGCN20489G001

Encompass_Preferred

Chemical. CAS 7512-17-6. Formula C8H15NO6. MW 221.2. Prepared by using chitin as a substrate. N-Acetyl-D-glucosamine D-GlcNAc is a non-toxic derivatized glucose monosaccharide found in polymers Peptidoglycan PGN of bacterial cell walls, chitin e.g. fungi, invertebrates, crustaceans, hyaluronic acids and various glycans. It is also synthesized in the glycosylation pathway as uridine diphosphate UDP-GlcNAc, which can then be released following degradation of glycosylated proteins. Atypical microbial danger signal that acts as a new activator of NLRP3 inflammasome by dissociating the enzyme hexokinase from the mitochondria. D-GlcNAc inhibits purified hexokinase, which is also involved in the glucose metabolism and obesity in mM range. For hexokinase dissociation from the mitochondria much higher concentrations are needed. Acceptor substrate for galactosyltransferases.

Catalog No. 50-256-2510


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