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Cayman Chemical N-acetyl-L-GlutamIn 100g

Supplier: Cayman Chemical 35398100 G

An inhibitor of USP7 (IC50 0 75 UM) selective for USP7 over USP47 and USP5 (IC50s 20 3 and 200 UM respectively) enhances ubiquitination of the USP7 substrate MDM2 in HCT116 colon cancer cells (IC50 0 23 UM) reduces cell viability in a panel of 108 cell lines (IC50s 10 UM for all) enhances apoptosis induced by doxorubicin or cisplatin in MCF-7 and U2OS cancer cells respectively
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