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Medchemexpress LLC N-Acetylmuramic acid | 10597-89-4 | 99.9% | 293.27 | 5 MG
SDP

Catalog No. 5000452629
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N-Acetylmuramic acid is a component of the bacterial cell wall peptidoglycan, crucial for maintaining cell shape and integrity. It inhibits spore germination by targeting a coat-associated hexosaminidase and a core enzyme. This compound is required for the proliferation and maintenance of cell shape in *Bacteroides forsythus*. Additionally, N-Acetylmuramic acid has demonstrated anti-inflammatory activity by inhibiting the p38 MAPK/NF-κB signaling pathway and is orally active.

  • Destroys cell wall, enabling normal growth and typical filamentous morphology in *B. forsythus*.
  • Reduces the expression of iNOS and COX-2, and inhibits the secretion of TNF-α and IL-1β in LPS-stimulated RAW264.7 cells.
  • Inhibits *E. coli*-induced intestinal villus edema and thickening in mice, exhibiting anti-inflammatory activity.

Catalog No. 50-004-52629 Supplier Medchemexpress LLC Supplier No. HYW0092745MG
May include imposed supplier surcharges.
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N-Acetylmuramic acid is a component of the bacterial cell wall peptidoglycan, crucial for maintaining cell shape and integrity. It inhibits spore germination by targeting a coat-associated hexosaminidase and a core enzyme. This compound is required for the proliferation and maintenance of cell shape in *Bacteroides forsythus*. Additionally, N-Acetylmuramic acid has demonstrated anti-inflammatory activity by inhibiting the p38 MAPK/NF-κB signaling pathway and is orally active.

  • Destroys cell wall, enabling normal growth and typical filamentous morphology in *B. forsythus*.
  • Reduces the expression of iNOS and COX-2, and inhibits the secretion of TNF-α and IL-1β in LPS-stimulated RAW264.7 cells.
  • Inhibits *E. coli*-induced intestinal villus edema and thickening in mice, exhibiting anti-inflammatory activity.

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