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Medchemexpress LLC N-(acid-PEG3)-N-bis(PEG3-azide) | 2182602-17-9 | 98.07% | C25H49N7O11 | 250 MG
Supplier: Medchemexpress LLC 250MGHY140520
N-(acid-PEG3)-N-bis(PEG3-azide) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group. This allows it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules that contain Alkyne groups, or in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Composed of two different ligands connected by a linker
- One ligand targets an E3 ubiquitin ligase
- The other targets the protein of interest
- Operates by harnessing the intracellular ubiquitin-proteasome system
- Facilitates the selective degradation of target proteins
- Intended for research use only
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